• Crowe Lab 2009


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  • Dr. Crowe will present his lecture, "Next Generation Vaccines" on Thursday, May 22, at 4 pm in 208 Light Hall as a part of Vanderbilt's Discovery Lecture series. This series seeks to respond to the requests of the Biomedical Advisory Board in presenting discussion-stimulating topics in research. Dr. Borden Lacy and Dr. Simon Mallal will also present findings that showcase Vanderbilt University's position on the cutting-edge of medical research; their lectures are respectively entitled "Structure and Function of Clostridium difficile Toxins A and B" and "Personalized Immunology." Learn more about the Discovery Lecture series.
  • Wen X, Krause JC, Leser JC, Lamb RA, Williams JV, Crowe JE Jr, Jardetsky TS. The structure of the human metapneumovirus fusion protein in complex with a human neutralizing antibody. In press, Nature Structural and Molecular Biology 2012.
  • Lindquist ME, Mainou B, Dermody T, Crowe JE Jr. Activation of protein kinase R is required for induction of stress granules by respiratory syncytial virus but dispensable for viral replication. Virology 2011; 413:103–110. PMID: 21377708.
  • Krause JC, Tsibane T, Tumpey TM, Huffman CJ, Briney BS, Smith SA, Basler CF, Crowe JE Jr. Epitope-specific human antibody repertoires diversify by B cell intraclonal sequence divergence and interclonal convergence. Journal of Immunology 2011; 187:3704-11. PMC3178754.
  • Krause JC, Tsibane T, Tumpey TM, Huffman CJ, Basler CF, Crowe JE Jr. A broadly neutralizing human monoclonal antibody that recognizes a conserved, novel epitope on the globular head of influenza H1N1 virus hemagglutinin. Journal of Virology 2011; 85:10905-08. PMID: 21849447.
  • Joyner AS, Willis JR, Crowe JE Jr, Aiken C. Maturation-induced cloaking of neutralization epitopes on HIV-1 particles. PLoS Pathogens 2011; 7(9): e1002234. doi:10.1371/journal.ppat.1002234
  • Dochow M, Krumm SA, Crowe JE Jr, Moore ML, Plemper RK. Independent structural domains in paramyxovirus polymerase proteins. Journal of Biological Chemistry 2012, 10.1074/jbc.M111.325258, Jan 3. [Epub ahead of print] PMID: 22215662
  • Engelhardt BG, Griffith ML, Crowe JE Jr, Savani BN, Kassim AA, Lu P, Weitkamp JH, Moore D, Yoder S, Rock MT, Jagasia SM, Jagasia M. Predicting post-transplant diabetes mellitus by regulatory T cell phenotype: Implications for metabolic intervention to modulate alloreactivity. Blood 2012 Jan 19. [Epub ahead of print] PMID: 22262764.
  • Zhang GL, Ansari HR, Bradley P, Cawley GC, Hertz T, Hu X, Huang JC, Jojic N, Kim Y, Kohlbacher O, Lund O, Lundegaard C, Magaret CA, Nielsen M, Papadopoulos H, Raghava GPS, Tal V-S, Xue L, Yanover C, Zhang H, Zhu S, Rock MT, Crowe JE Jr, Panayiotou C, Polycarpou MM, Duch W, Brusic V. Machine learning competition in immunology – Prediction of HLA class I molecules. Journal of Immunological Methods 2011; 374:1-4.
  • Rock MT, McKinney BA, Yoder SM, Prudom CE, Wright DW, Crowe JE Jr. Identification of potential human respiratory syncytial virus and metapneumovirus T cell epitopes using computational prediction and MHC binding assays. Journal of Immunological Methods 2011; 374:13-17. NIHMS323653.
  • Krause JC, Ekiert DC, Tumpey TM, Smith PB, Wilson IA, Crowe JE Jr. An insertion mutation that distorts antibody binding site architecture enhances function of a human antibody. mBio 2011; 2(1):e00345-10. doi:10.1128/mBio.00345-10. PMCID: 3037006.
  • Shaikh FY, Cox RG, Lifland AW, Hotard AL, Williams JV, Moore ML, Santangelo PJ, Crowe JE Jr. A critical phenylalanine residue in the respiratory syncytial virus fusion protein cytoplasmic tail mediates assembly of internal viral proteins into viral filaments and particles. mBio 2012; 3(1):e00270-11. doi: 10.1128.
  • Smith SA, Zhou Y, Olivarez NP, Broadwater AH, de Silva AM, Crowe. Persistence of circulating B memory cell clones with potential for dengue virus disease enhancement for decades following infection. Journal of Virology 2011 Dec 14. [Epub ahead of print] PMID: 22171265.